TMEM258, transmembrane protein 258, 746

N. diseases: 63; N. variants: 37
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs102275
rs102275 		0.827 0.320 11 61790331 non coding transcript exon variant T/C snv 0.47
CUI: C0523829
Disease: Phosphatidylcholine measurement
Phosphatidylcholine measurement 		0.700 1.000 1 2019 2019
dbSNP: rs102275
rs102275 		0.827 0.320 11 61790331 non coding transcript exon variant T/C snv 0.47
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement 		0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C2677123
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C1319315
Disease: Adenocarcinoma of large intestine
Adenocarcinoma of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C1837315
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C0346629
Disease: Malignant neoplasm of large intestine
Malignant neoplasm of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C3554460
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		0.700 1.000 1 2019 2019
dbSNP: rs174533
rs174533 		0.763 0.160 11 61781553 intron variant G/A snv 0.37 0.29
CUI: C2675481
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		0.700 1.000 1 2019 2019
dbSNP: rs174535
rs174535 		0.776 0.280 11 61783884 missense variant T/A;C;G snv 0.38 0.32
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.700 1.000 1 2019 2019
dbSNP: rs174535
rs174535 		0.776 0.280 11 61783884 missense variant T/A;C;G snv 0.38 0.32
CUI: C0741260
Disease: Adult onset asthma
Adult onset asthma 		0.700 1.000 1 2019 2019
dbSNP: rs174535
rs174535 		0.776 0.280 11 61783884 missense variant T/A;C;G snv 0.38 0.32
CUI: C0428568
Disease: Fasting blood glucose measurement
Fasting blood glucose measurement 		0.700 1.000 1 2019 2019
dbSNP: rs174535
rs174535 		0.776 0.280 11 61783884 missense variant T/A;C;G snv 0.38 0.32
CUI: C0035242
Disease: Respiratory Tract Diseases
Respiratory Tract Diseases 		Respiratory Tract Diseases 0.700 1.000 1 2019 2019
dbSNP: rs174535
rs174535 		0.776 0.280 11 61783884 missense variant T/A;C;G snv 0.38 0.32
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps 		Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases 0.700 1.000 1 2019 2019
dbSNP: rs174537
rs174537 		0.708 0.400 11 61785208 non coding transcript exon variant G/T snv 0.28
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2019 2019
dbSNP: rs174529
rs174529 		11 61776489 intron variant T/C snv 0.34
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.700 1.000 2 2018 2019
dbSNP: rs102274
rs102274 		1.000 0.080 11 61790354 non coding transcript exon variant T/C snv 0.28
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2018 2018
dbSNP: rs102274
rs102274 		1.000 0.080 11 61790354 non coding transcript exon variant T/C snv 0.28
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2018 2018
dbSNP: rs102275
rs102275 		0.827 0.320 11 61790331 non coding transcript exon variant T/C snv 0.47
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2018 2018
dbSNP: rs102275
rs102275 		0.827 0.320 11 61790331 non coding transcript exon variant T/C snv 0.47
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs102275
rs102275 		0.827 0.320 11 61790331 non coding transcript exon variant T/C snv 0.47
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2018 2018
dbSNP: rs11320420
rs11320420 		1.000 0.080 11 61774535 intron variant AAAAA/-;AAA;AAAA;AAAAAA delins 0.30
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2018 2018